Supplementary data for BTS 2020 poster P30

Numbers of transplants by R and D status

Proportions of transplants by donor category

Total inpatient stay

Analysis of variance showed both donor and recipient category had a statistically significant effect on total inpatient stay.

             Df Sum Sq Mean Sq F value  Pr(>F)   
Rec_Cat       3   6899  2299.8   3.884 0.00959 **
Donor_Cat     3   6401  2133.8   3.604 0.01393 * 
Residuals   279 165206   592.1                   
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

Numbers of readmissions

R4 recipients: eGFR by donor category

eGFR at 1 year

Analysis of variance, with TukeyHSD post-hoc tests, showed that the lower eGFR at 1 year for R4 recipients receiving D4 kidneys was statistically significant vs R4 recipients receiving D1, D2 or D3 kidneys.

             Df Sum Sq Mean Sq F value   Pr(>F)    
Donor_Cat     3  17172    5724   9.923 4.31e-06 ***
Residuals   182 104988     577                     
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
9 observations deleted due to missingness
  Tukey multiple comparisons of means
    95% family-wise confidence level

Fit: aov(formula = eGFR_1yr ~ Donor_Cat, data = r4.df)

$Donor_Cat
             diff       lwr        upr     p adj
D2-D1  -7.7296104 -22.18746   6.728239 0.5095748
D3-D1  -8.2914286 -24.08143   7.498576 0.5251059
D4-D1 -25.2096639 -39.19353 -11.225801 0.0000337
D3-D2  -0.5618182 -14.02758  12.903943 0.9995454
D4-D2 -17.4800535 -28.77390  -6.186210 0.0005038
D4-D3 -16.9182353 -29.87376  -3.962707 0.0047795

eGFR at 2 years

Analysis of variance, with TukeyHSD post-hoc tests, showed that the lower eGFR at 2 years for R4 recipients receiving D4 kidneys was statistically significant vs R4 recipients receiving D1, D2 or D3 kidneys:

             Df Sum Sq Mean Sq F value  Pr(>F)    
Donor_Cat     3  13442    4481   7.388 0.00011 ***
Residuals   171 103717     607                    
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1
20 observations deleted due to missingness
  Tukey multiple comparisons of means
    95% family-wise confidence level

Fit: aov(formula = eGFR_2yr ~ Donor_Cat, data = r4.df)

$Donor_Cat
            diff       lwr          upr     p adj
D2-D1 -12.978431 -28.18587   2.22901169 0.1234946
D3-D1 -10.046078 -26.51706   6.42490175 0.3913551
D4-D1 -25.028571 -39.72612 -10.33102077 0.0001032
D3-D2   2.932353 -11.21453  17.07923667 0.9496855
D4-D2 -12.050140 -24.08588  -0.01439636 0.0496021
D4-D3 -14.982493 -28.57977  -1.38521422 0.0244694

R4 recipients: survival by donor category