The uncertain significance of elevated transaminases after renal transplantation
Sean McCafferty, Siobhan McManus, Karen Stevenson, John Asher
02/03/2020
Supplementary data for BTS 2020 poster P133
Summary of post-translant transaminases
The summary statistics for pre-transplant serum ALT, maximum ALT and AST in first seven days post transplant and maximum AST:ALT ratio are provided below:
| Pre_ALT | Max_ALT | Max_AST | AST_ALT_ratio | |
|---|---|---|---|---|
| Min. : 5.00 | Min. : 8.00 | Min. : 9.00 | Min. :0.3137 | |
| 1st Qu.: 12.00 | 1st Qu.: 25.50 | 1st Qu.: 24.00 | 1st Qu.:0.6727 | |
| Median : 16.00 | Median : 39.00 | Median : 34.00 | Median :0.8723 | |
| Mean : 19.47 | Mean : 62.97 | Mean : 51.98 | Mean :0.9640 | |
| 3rd Qu.: 22.00 | 3rd Qu.: 66.50 | 3rd Qu.: 55.00 | 3rd Qu.:1.1463 | |
| Max. :175.00 | Max. :2439.00 | Max. :2017.00 | Max. :3.7273 | |
| NA’s :187 | NA | NA | NA |
Relationship of ALT to CIT
The boxplot and scatter plot show the (lack of) relationship between the peak ALT level and cold ischaemic time.
Peak ALT and duration of DGF
The relationship between peak ALT and the duration of delayed graft function in days:
ALT and donor type
Numbers in each ALT group
| ALT.class | Number |
|---|---|
| Normal | 619 |
| 40-100 | 375 |
| 100-200 | 124 |
| 200-300 | 31 |
| >300 | 17 |
Peak ALT and post-op day
Relationship of peak ALT to ALT at 14 days
Relationship of peak AST to AST at 14 days
Relationship of peak bilirubin to bilirubin at 14 days
Relationship of peak PT to PT at 14 days
